Issue 3

Article 1 of 5On Alpha¹

Transient contractility attenuation reprograms epithelial cells into a protrusion-driven state that drives tissue fluidization

Summary

Jammed epithelial cells get a quirky blebbistatin chill pill on their contractility, flipping them into protrusion-happy movers that fluidize the tissue like a molecular rave turning stiff crowds into flowing, ERK-rewired party animals with boosted traction.

Community Discussion

Shared by Tsuyoshi Hirashima (@hirashima0203) with mesmerizing live-imaging video; it sparked questions and congrats from mechanobiology and cell migration researchers

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Transient contractility attenuation reprograms epithelial cells into a protrusion-driven state that drives tissue fluidization

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Kaimen Rigor, on the record.