Αlpha¹

Issue 2

From xenobots with memories, world model for cells, to RNA-Seq analyses speedup using GPUs

March 24, 20266 ArticlesAlpha¹ Editorial

Behavioral, Physiological, and Transcriptional Mechanisms of Memory in a Synthetic Living Construct

Summary

Imagine a blob of frog skin with no brain that can still "remember" things. These "xenobots" use weird calcium waves to store memories of chemical hits for days. It’s basically a biological hard drive made of lab-grown slime—proving you don't actually need a brain to have a memory.

Community Discussion

Sparked massive hype among synthetic biologists and roboticists, posted by Michael Levin (@drmichaellevin) with 21 replies debating non-neural cognition

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Issue 2

Behavioral, Physiological, and Transcriptional Mechanisms of Memory in a Synthetic Living Construct

Towards building a World Model to simulate perturbation-induced cellular dynamics by AlphaCell

RNA-seq analysis in seconds using GPUs

An Energy Landscape Approach to Miniaturizing Enzymes using Protein Language Model Embeddings

CellSweep: Decontaminating Ambient RNA and Barcode Swapping in Single-Cell Data

In vivo multiomic Perturb-seq with enhanced nuclear gRNA capture

Rigor Review and Alpha1 Selection, together.